Neurodegenerative Diseases are a group of mostly gradual, congenital or sporadic diseases of the nervous system. A characteristic feature is the damage of neurons causing various neurologic symptoms leading in many cases to dementia and movement disorders. These diseases occur in different age ranges, and cause characteristic histologic damage in the brain that can be either localised in one region or spread across multiple regions. Examples of neurodegenerative diseases are Alzheimer and Parkinson disease.
The frequency of neurodegenerative diseases is possibly going to increase more and more in the future due to increased life expectancy. Currently, more than 30 million people are affected by these diseases worldwide. In Germany alone about one million patients suffer from dementia. So far there is no established therapy to prevent the progression of the disease.
Epilepsy is a disease with spontaneously developed spasms. Epileptic seizures are the consequence of synchronic discharges of groups of neurones in the brain. This leads to involuntary stereotypical behaviour and health disorders. Worldwide more than 50 million people are impacted by this disease. Epilepsy has various effects on the every day life of the patients which should also be considered in the treatment.